Pyruvate Metabolism

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Pyruvate metabolism in Sarcina maxima.

The mechanisms of pyruvate cleavage and hydrogen production by Sarcina maxima were studied. It was found that a phosphoroclastic system for pyruvate oxidation, similar to that occurring in saccharolytic clostridia, is present in S. maxima. Cleavage of pyruvate by extracts of the latter organism resulted in the formation of acetyl phosphate, CO(2), and electrons which were transferred to ferredo...

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Pyruvate metabolism in mammalian liver.

PARLI, C. JOHN, LINDA C. BURNS, SHARADCHANDRA K. MEGHAL, KEITH KINNEBERG, ROBERT M. OWEAL, AND ROGER E. KOEPPE. Pyruvate metabolism in mammalian liver. Am. J. Physiol. 216(6) : 1525-l 533. 1969.-Labeling patterns were determined in I) liver and carcass protein glutamate of glucocorticoid-treated rats and fed or fasted rats, mice, rabbits, hamsters, and guinea pigs from pyruvate-Z-14C; 2) free l...

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Pyruvate metabolism in Lactobacillus brevis.

The pyruvate metabolism of LactobaciUus plantarum and Latobacillus arabino8su, which according to Bergey (1948) are identical organisms, has been studied by Rowatt (1951) and Nossal (1952). Both these homofermentative lactobacilli were shown to form 3-hydroxybutan-2-one (acetoin) as the main product of their pyruvate metabolism. No one appears to have studied the metabolism of pyruvate by any o...

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Pyruvate and propionate metabolism in lactating cows. Effect of butyrate on pyruvate metabolism.

The glucogenic behavior of butyrate in ruminants has been reported frequently, but the metabolic nature of this anomalous relationship has remained obscure. To test the possibility that the metabolism of butyrate affects gluconeogenesis, lactating cows were given intravenous injections of tracer amounts of pyruvate-2-14C and, in parallel experiments, of pyruvate-2-l% plus substrate amounts of s...

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The metabolism of pyruvate in the tricarboxylic acid cycle. II. Tissue characteristic metabolism of pyruvate.

It has been shown previously that the mode of entrance of pyruvate into the tricarboxylic acid cycle of the liver is influenced by the nutritional status of the animal. The distribution of isotopic carbon in glutamic acid after the administration of alanine-2-Cl4 or pyruvate-2-Cl4 is reproducible in a series of rats in the same nutritional status (1, 2). This report describes a comparative stud...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1958

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)64656-3